PLASMON RESONANCE (PR) SYSTEM AND INSTRUMENT, DIGITAL MICROFLUIDIC (DMF) CARTRIDGE, AND METHODS OF USING LOCALIZED SURFACE PLASMON RESONANCE (LSPR) FOR ANALYSIS OF ANALYTES

摘要

A plasmon resonance (PR) system and instrument, digital microfluidic (DMF) cartridge, and methods of using localized surface plasmon resonance (LSPR) and droplet operations for analysis of analytes is disclosed. For example, a PR system is provided that may include a DMF cartridge that may support both fixed LSPR sensing capability and in-solution LSPR sensing capability for analysis of analytes. The DMF cartridge may include an electrode arrangement for performing droplet operations, wherein the droplet operations can be used for performing fixed LSPR sensing operations and in-solution LSPR sensing operations. Further, methods of using droplet operations in the DMF cartridge to perform fixed LSPR sensing operations and/or in-solution LSPR sensing operations are provided.