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Netrin-1 Compounds and Compositions Thereof for Treating Pulmonary Hypertension
Netrin-1 Compounds and Compositions Thereof for Treating Pulmonary Hypertension
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机译:用于治疗肺动脉高压的Netrin-1化合物和组合物
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摘要
Disclosed herein are netrin-1 compounds and compositions thereof and methods of using thereof to treat pulmonary hypertension. In some embodiments, the present invention provides methods of treating, reducing, or inhibiting pulmonary hypertension or reducing a subjects mean pulmonary arterial pressure (mPAP) and/or the subjects right ventricular systolic pressure (RVSP), which methods comprise administering to the subject a therapeutically effective amount of one or more netrin-1 compounds.
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