THERMAL CYCLER DEVICE FOR IMPROVING HEAT TRANSFER UNIFORMITY AND THERMAL HISTORY CONSISTENCY

摘要

A thermal cycler device for PCR is provided, including an annular conveying element (60) having a circular conveying path, a plurality of slide plate device holding elements (30), a plurality of heating blocks (50), a pressing element (10) comprising a plurality of pressing blocks (20) and a cooling device. The annular conveying element (60) is configured to operate in stages, such that the slide plate device holding elements (30) move along the circular conveying path while carrying a plurality of slide plate devices. When each slide plate device holding element (30) moves to the corresponding heating block (50), the annular conveying element (60) stops operating and the pressing element (10) performs a pressing process, such that each slide plate device contacts the corresponding heating block (50) for heat transfer. This may improve heat transfer uniformity and thermal history consistency.