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Sulfonyl-substituted isoquinolines as inhibitors of RHO kinase and hERG potassium channel activity

机译:磺酰基取代的异喹啉作为rhO激酶和Herg钾沟道活性的抑制剂

摘要

Disclosed are a class of isoquinoline compounds acting as RHO protein kinase inhibitors, and the use thereof in the preparation of a drug for treating diseases associated with RHO protein kinase. Particularly disclosed are compounds as shown in formula (I) and pharmaceutically acceptable salts thereof.;
机译:公开了一种作为Rho蛋白激酶抑制剂的异喹啉化合物,以及其用途在制备用于治疗与Rho蛋白激酶相关的疾病的药物中。 特别公开的是如式(I)中所示的化合物及其药学上可接受的盐;

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