首页> 外国专利> ANTICANCER ADJUVANT AND PHARMACEUTICAL COMPOSITION FOR TREATING ANTICANCER-AGENT-RESISTANT CANCER, AND KIT COMPRISING SAME

ANTICANCER ADJUVANT AND PHARMACEUTICAL COMPOSITION FOR TREATING ANTICANCER-AGENT-RESISTANT CANCER, AND KIT COMPRISING SAME

机译:用于治疗抗癌患者的抗癌辅助和药物组合物,以及包含该抗癌的试剂盒

摘要

The present invention relates to an anticancer adjuvant for treating anticancer-agent-resistant cancer, and a pharmaceutical composition containing same. If resistance to DNA replication inhibitory anticancer agents is exhibited, a substance for inhibiting the activity of tristetraprolin can be included as an anticancer adjuvant so as to maximize the effects of an anticancer agent, and thus is usable in cancer treatment. In addition, the present invention relates to a composition, a kit and a method for diagnosing resistance to DNA replication inhibitory anticancer agents, and the resistance to the anticancer agents can be identified by measuring the expression level of tristetraprolin.
机译:本发明涉及一种用于治疗抗癌剂抗性癌症的抗癌佐剂,以及含有该抗癌癌的药物组合物。 如果表现出对DNA复制抑制性抗癌剂的耐药性,则可以包含用于抑制三唑啉醇活性的物质作为抗癌佐剂,以便最大化抗癌剂的影响,因此可用于癌症治疗。 此外,本发明涉及组合物,试剂盒和用于诊断DNA复制抑制性抗癌剂的方法,并且通过测量三分列的表达水平,可以通过测量Tristetraprolin的表达水平来鉴定对抗癌剂的抗性。

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