首页>
外国专利>
ACE2-TARGETED COMPOSITIONS AND METHODS FOR TREATING COVID-19
ACE2-TARGETED COMPOSITIONS AND METHODS FOR TREATING COVID-19
展开▼
机译:ACE2靶向组合物和治疗Covid-19的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
This invention provides a monoclonal antibody that (i) specifically binds to the extracellular portion of human angiotensin converting enzyme 2 (hACE2); (ii) specifically inhibits binding of SARS-CoV-2 to the extracellular portion of hACE2; and (iii) does not significantly inhibit the ability of hACE2 to cleave angiotensin II and/or a synthetic MCA-based peptide. This invention also provides related recombinant AAV vectors, recombinant AAV particles, compositions, prophylactic and therapeutic methods, and kits.
展开▼