Sensor holder for using a conventional sensor with a single-use bioreactor while maintaining the sterility of the single-use bioreactor

摘要

The invention relates to a bioreactor system (1), with: a pre-sterilized disposable bioreactor (2) having a reactor wall (20) which surrounds an interior (21) of the disposable bioreactor (2), the interior (21) for receiving a fluid medium (M ) is designed, a sensor (3), which can in particular be an unmodified standard sensor, wherein the sensor is designed to detect a gaseous analyte or an analyte dissolved in the medium (M), wherein the sensor (3) has a sensor housing (30) with an external thread (31) and a sensor shaft (32), the sensor shaft (32) having a distal end section (33) with an end face (34) which is one for the analyte permeable area (35), a sensor receptacle (4) connected to the reactor wall (20) and designed to accommodate the sensor (3) in such a way that the sterility of the disposable bioreactor (2) is maintained, the sensor receptacle hme (4) has a circumferential flange (40) via which the sensor receptacle (4) is fixed to the reactor wall (20), the flange (40) having a circumferential inner side (41) with an internal thread (42) into which the external thread (31) of the sensor housing (30) can be screwed in, and the sensor receptacle (4) has a wall (43) connected to the flange (40) which, together with the sensor shaft (32), extends into the interior (21) of the disposable bioreactor (2 ) protrudes and separates the sensor (3) from the interior (21) when the sensor (3) is arranged in the sensor holder (4) and its external thread (31) is screwed into the internal thread (42) of the sensor holder (4) as intended is.