NANOSTRUCTURED NANOPARTICLES COMPRISING ONE OR MORE ACTIVE INGREDIENTS FOR THE TREATMENT OF DISEASES CAUSED BY TRYPANOSOMES AND FOR THE TREATMENT OF TUMOURS OF NEURAL ORIGIN, COMPOSITIONS COMPRISING SAME, A PREPARATION METHOD AND THERAPEUTIC USE THEREOF

摘要

Pharmaceutical composition of antineoplastic and anti-tumor action, and method of obtaining it, wherein said composition comprises structured lipid nanoparticles that are between 0.1 nm and 100 nm in diameter, spheroidal in shape and contain particles of one or more active substances for the treatment of diseases produced by tripanosomes and for the treatment of tumors of neural origin, and at least one coupling of two fatty acids consisting of a saturated fatty acid or semi-solid lipid at the temperature between 19° C. and 21° C. and an unsaturated or liquid fatty acid at the temperature between 19° C. and 21° C. and in turn the method of obtaining finally contains the nanoparticles of one or more active substances for trypanosomiasis in colloidal suspension, the Z potential ranges from −30 to +30, preferably +8, the particles measured by Z-sizer and ultramicroscopy have from 0.1 nanometers to 100 nanometers, preferably 1 nanometer in diameter and spheroidal shape.