METHOD FOR DIAGNOSING BREAST CANCER VIA MICROBIAL METAGENOMIC ANALYSIS

摘要

The present invention relates to a method of diagnosing breast cancer through bacterial and archaeal metagenomic analysis, and more particularly, a method of diagnosing breast cancer by analyzing an increase or decrease in content of extracellular vesicles derived from specific bacteria and archaea through bacterial and archaeal metagenomic analysis using a sample derived from a subject. Extracellular vesicles secreted from bacteria or archaea present in the environment are absorbed into the human body, and thus may directly affect the occurrence of cancer, and it is difficult to diagnose breast cancer early before symptoms occur, and thus efficient treatment therefor is difficult. Thus, according to the present invention, a risk of developing breast cancer may be predicted through bacterial and archaeal metagenomic analysis using a human body-derived sample, and thus the onset of breast cancer may be delayed or breast cancer may be prevented through appropriate management by early diagnosis and prediction of a risk group for breast cancer, and, even after breast cancer occurs, early diagnosis for breast cancer may be implemented, thereby lowering the incidence rate of breast cancer and increasing therapeutic effects.