ISOLATED POLYPEPTIDE OF THE TOXIN A AND TOXIN B PROTEINS OF C. DIFFICILE AND USES THEREOF

摘要

This present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of C.difficile toxin A and toxin B as set forth in the amino acid sequences of SEQ ID NO:2 and SEQ ID NO:4. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides may be used to neutralize toxic effects of C.difficile toxin A and/or toxin B.