C. A B Isolated polypeptide of the Toxin A and Toxin B proteins of C. Difficile and uses thereof

摘要

The present invention provides C-TAB.G5 and C-TAB.G5.1 isolated polypeptides comprising the receptor binding domains of the C. difficile A toxin and the B toxin described in the amino acid sequences of SEQ ID NO: 2 and SEQ ID NO: 4 do. The C-TAB.G5 and C-TAB.G5.1 isolated polypeptides can be used to neutralize the toxic effects of C. difficile A toxin and / or B toxin.