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Methods of non-destructive nanostraw intracellular sampling for longitudinal cell monitoring
Methods of non-destructive nanostraw intracellular sampling for longitudinal cell monitoring
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机译:纵向细胞监测的非破坏性纳秒细胞内采样方法
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摘要
Methods and apparatuses to non-destructively and periodically sample a small quantity of intracellular proteins and mRNA from the same single cell or cells for an extended period of time. Specifically, describe herein are non-perturbative methods for time-resolved, longitudinal extraction and quantitative measurement of intracellular proteins and nucleic acids from a variety of cell types using systems including nanostraws.
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