ACOUSTIC-ELECTRIC STIMULATION NEUROMODULATION THERAPY AND APPARATUS COMBINING ELECTROENCEPHALOGRAM TESTING, ANALYSIS AND CONTROL

摘要

Provided are a noninvasive acoustic-electric stimulation neuromodulation method and apparatus combining electroencephalogram objective testing, analysis, feedback and control. The apparatus comprises: an electroencephalogram testing and signal processing and analysis system (2), an intelligent diagnosis and therapy control system (1), an acoustic stimulation therapy system (4), a transcranial electrical pulse stimulation therapy system (3) and a cognitive behavior psychotherapy system (5). Electroencephalogram testing of a plurality of brain functional regions of a human body is performed before, during and after noninvasive acoustic stimulation and/or electrical pulse stimulation and/or cognitive psychotherapy; and a correlation model including a therapeutic effect evaluation is established by means of electroencephalogram signal collection, real-time electroencephalogram spatio-temporal modeling and objective analysis of characteristic parameters of a neural network, thereby realizing a closed loop of testing, analysis, feedback, therapy and modulation. According to the method and the apparatus, a tracking, objective evaluation and prediction method for the effects of neuromodulation therapy over multiple courses or multiple sessions can be formed, and according to the expected therapeutic effects, a subsequent method for therapeutic schedule implementation and scheme parameter selection is qualitatively and quantitatively modulated and optimized, and a neurological function state can be objectively evaluated and predicted.