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TOPICAL USE OF ERLOTINIB FOR TREATING KERATODERMAS IN CHILDREN

机译:替代尔洛尼替尼治疗儿童角质节病药的局部使用

摘要

The present invention relates to a topical composition comprising erlotinib and a pharmaceutically acceptable excipient for use in the treatment of a keratoderma in a child, preferably a palmoplantar keratoderma (PPK), wherein the composition is topically administered. According to one embodiment, the composition further comprises a penetration enhancer. According to one embodiment, the treated subject is younger than three years old. The present invention also relates to woven or non-woven fabric support comprising erlotinib and to dressings, patches, gloves and socks comprising the support useful in the treatment of a PPK.
机译:本发明涉及一种局部组合物,其包含Erlotinib和用于治疗儿童的角蛋白,优选棕榈术角酸酯(PPK)的药学上可接受的赋形剂,其中局部施用组合物。 根据一个实施方案,组合物还包含渗透增强剂。 根据一个实施例,治疗的受试者年龄小于三岁。 本发明还涉及包含厄洛替尼和敷料,贴片,手套和袜子的织造或非织造织物支撑件,所述敷料,贴片,手套和袜子包括可用于治疗PPK的助剂。

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