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Treatment of metabolic disorders using a binding protein for gastric inhibitory peptide receptor (GIPR) combined with GLP-1 agonist

机译:使用胃抑制肽受体(GIPR)结合GLP-1激动剂治疗代谢紊乱的代谢紊乱

摘要

Methods of treating metabolic diseases and disorders using antigen binding proteins specific for GIPR polypeptides are provided. In various embodiments, the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels, and diabetic nephropathy. In certain embodiments, the antigen binding protein is administered in combination with a GLP-1 receptor agonist.
机译:提供了使用针对GiPR多肽特异的抗原结合蛋白治疗代谢疾病和疾病的方法。 在各种实施方案中,代谢疾病或病症是2型糖尿病,肥胖,血脂血症,升高的葡萄糖水平,升高的胰岛素水平和糖尿病肾病。 在某些实施方案中,抗原结合蛋白与GLP-1受体激动剂组合施用。

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