Sequential approximations of sample analyte concentrations

摘要

To improve accuracy and/or precision of the analysis-determined pseudo-reference concentration through progressive approximation.SOLUTION: A method of determining analyte concentration in a sample is disclosed, comprising: generating at least two output signals from a sample; measuring at least two analyte responsive output signals from the sample; determining at least two initial analyte concentrations from the at least two analyte responsive output signals; determining at least one first anchor parameter corresponding to a first pseudo-reference concentration, where the at least one first anchor parameter compensates for system error; determining a second pseudo-reference concentration by averaging at least two first anchor compensated analyte concentrations, where the second pseudo-reference concentration is a second substitute for true relative error; and reporting the second pseudo-reference concentration as a final compensated analyte concentration of the sample.SELECTED DRAWING: None