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PLASMA KALLIKREIN INHIBITORS AND USES THEREOF FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME

机译:血浆Kallikrein抑制剂及其用途用于治疗急性呼吸窘迫综合症

摘要

Provided herein are methods for treating acute respiratory distress syndrome (ARDS), such as ARDS associated with respiratory virus infection, involving administering an inhibitor of the contact activation pathway. Also provided herein are methods for treating pneumonia and methods for reducing and/or preventing thrombosis associated with extracorporeal membrane oxygenation (ECMO) in a subject having acute respiratory distress syndrome (ARDS), involving administering an inhibitor of the contact activation pathway.
机译:本文提供了治疗急性呼吸窘迫综合征(ARDS)的方法,例如与呼吸道病毒感染相关的ARD,涉及给予接触活化途径的抑制剂。 本文还提供了用于治疗肺炎的方法和用于在具有急性呼吸窘迫综合征(ARDS)的受试者中,涉及施用接触活化途径的抑制剂的对象中减少和/或预防与体外膜氧合(ECMO)相关的血栓形成和/或预防血栓形成。

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