IMMTAC-binding CD3 and HLA-A*02 restriction peptides with extended half-life

摘要

The present invention relates to a T cell receptor (TCR), an immunoglobulin Fc domain or an albumin-binding moiety having specificity for an antigen; and soluble multi-domain binding molecules comprising an immune effector domain. Such multi-domain binding molecules are advantageous because they exhibit improved half-life while retaining function.