Peroxynitrite activity inhibitory method and peroxynitrite activity inhibitor screening method

摘要

PROBLEM TO BE SOLVED: To provide a method for inhibiting peroxynitrite activity and a method for screening an activity inhibitor, which can suppress the action of peroxynitrite excluding protein nitration reaction such as inhibition of cell differentiation / proliferation. A method for inhibiting the peroxynitrite activity of the epidermis by maintaining the pH of the epidermis below 6.5 and / or activating the nitration reaction of proteins in the epidermis. [Selection diagram] None