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METHOD AND COMPOSITIONS FOR ENHANCED ANTI-TUMOR EFFECTOR FUNCTIONING OF T CELLS
METHOD AND COMPOSITIONS FOR ENHANCED ANTI-TUMOR EFFECTOR FUNCTIONING OF T CELLS
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机译:用于增强T细胞的抗肿瘤效应器功能的方法和组合物
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摘要
Integration of costimulatory signaling domains within a tumor targeting chimeric antigen receptor (CAR), such as the IL13R±2 specific IL13-zetakine (IL13¶), enhances T cell-mediated responses against tumors even in the absence of expressed ligands for costimulatory receptors.
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