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CATIONIC LIPID COMPOUNDS AND COMPOSITIONS THEREOF FOR USE IN THE DELIVERY OF MESSENGER RNA
CATIONIC LIPID COMPOUNDS AND COMPOSITIONS THEREOF FOR USE IN THE DELIVERY OF MESSENGER RNA
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机译:用于递送信使RNA的阳离子脂质化合物及其组合物
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摘要
The compounds disclosed herein compound of Formula (I), substructures thereof, and pharmaceutically acceptable salts thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated with deficiency of one or more proteins.
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