TSLP topical composition comprising the extract of combined herbs comprising Longanae Arillus for TSLP inhibition and for the treatment or alleviation of skin inflammatory disease

摘要

The present invention relates to a composition for the prevention and/or alleviation and/or treatment of TLSP inhibition or inflammatory skin disease and skin itchiness, comprising as an active ingredient a combination herbal extract composed of longan meat, gobon and raw paper, and specifically, the combination herbal extract BALB/C in vivo effect test for atopic dermatitis using 6-week-old female mice (Experimental Example 1), GM-CSF, IL-4, IL-10, IL-13, IL-31, and IL-33, etc. Various experiments such as cytokine expression inhibitory effect test (Experimental Example 2), TSLP cytokine expression inhibitory effect test (Experimental Example 3), etc. were performed, and it was confirmed that the samples exhibit strong skin anti-inflammatory activity, etc. It can be used as a pharmaceutical composition or a cosmetic composition for external use on the skin for inflammation.