topical composition comprising the extract of combined herbs comprising Longanae Arillus for the treatment or alleviation of skin scar

摘要

The present invention relates to a composition for the prevention and/or alleviation and/or treatment of wounds containing a combination herbal extract composed of longan meat, Gobon, and raw paper as an active ingredient, and specifically, the combination herbal extract contains human skin epithelial cells (HaCaT). ) using the cytokine expression inhibitory effect experiment (experiment 1), the cell proliferation effect of the herbal mixture extract of the test (in vitro proliferation assay) (example 2); Skin wound healing effect test of herbal mixture extract ( In vitro wound healing assay) (Experimental Example 3); Chronic wound healing effect test of herbal mixture extract using diabetic model mouse (Experimental Example 4); Skin wound tissue recovery effect test of herbal mixture extract (Experimental Example 5); Various experiments, such as an experiment on the effect of the herbal mixture extract on the expression of growth factor-related inflammatory factors (Experimental Example 6), etc., were performed, and the samples confirmed the strong wound healing and improvement effect, and the composition was applied to the skin for wound treatment and improvement. It can be used as a pharmaceutical composition or a cosmetic composition.