System and method for analysis of alternative splicing

摘要

A stem and method for quantifying and analyzing alternative splicing events and for predicting the biological relevance of alternative splicing events.The genome provided by the userQuantifying alternative splicing events using biological data associated with transcriptome or bothQuantified alternative splicing eventsTo process the information stored in the databaseIdentify statistically significant alternative splicing eventsProtein structureProtein functionRNA stabilityRNA integrityOr to predict the functional impact of alternative splicing events on biological pathwaysA system and method is generally disclosed which uses a statistical modeling and machine learning algorithm to perform the steps of predicting the feasibility of drug discovery and reversibility and splicing of an abnormal splicing event.