Application of recombinant RR2 protein or RyR2 recombinant protein in the manufacture of antiheart failure medicine

摘要

In the field of Biomedical Engineering, the RyR2 protein or ry in the manufacture of antiheart failure medicineRR2 recombinant proteins are naturally presentAn YR2 protein fragment or variant, e.g., spry of the natural RyR2 protein1 domain protein, P1 domain protein, spry2 domain protein, SPRY1 domain protein, domain domain protein, HD1 domain proteinDomain name proteinProtein kinase, u-motif protein, P2 domain protein, P2 domain fragment proteinMay be a quality 1, P2 domain fragment protein 2 or RyR2 protein P2 mutantExogenous RyR2 recombinant protein is a normal small animal model and a small animal disease modelHigh expression levels in the left ventricular ejection fraction of experimental animals differed in degreesHowever, in the disease model animal, the degree of difference is different from the control group, and β Address listIt is possible to decrease the ventricular tachyarrhythmia triggered inThe cardiac function of the group is recovered.Diagram