首页> 外国专利> USE OF 3-(4-HYDROXYPHENYL)PROPIONIC ACID IN PREPARATION OF DRUGS FOR PREVENTING AND TREATING RESPIRATORY TRACT INFECTION

USE OF 3-(4-HYDROXYPHENYL)PROPIONIC ACID IN PREPARATION OF DRUGS FOR PREVENTING AND TREATING RESPIRATORY TRACT INFECTION

机译:使用3-(4-羟基苯基)丙酸在制备用于预防和治疗呼吸道感染的药物中

摘要

The present invention relates to new medicine application of p-hydroxyphenylpropio nic acid. Experiments prove that p-hydroxyphenylpropionic acid has a remarkable pharmacological effect in inhibiting respiratory tract infection, particularly inhibiting pulmonary edema, inflammatory cell infiltration and cell apoptosis in lung injury and delaying lung function degradation of mice. Therefore, the present invention discloses the application of p-hydroxyphenylpropionic acid to prepare a medicine for preventing and treating respiratory tract infection, particularly pneumonia, pulmonary edema or pulmonary epithelial and/or endothelial cell necrosis in lung injury for the first time.
机译:本发明涉及对羟基苯基丙酸的新药施用。 实验证明,对羟基苯基丙酸具有显着的药理学作用,抑制呼吸道感染,特别是抑制肺部水肿,肺部损伤的肺部水肿,炎性细胞浸润和细胞凋亡,延迟小鼠的肺功能降解。 因此,本发明公开了对羟基苯基丙酸的应用,制备用于预防和治疗呼吸道感染,特别是肺损伤的呼吸道感染,特别是肺炎,肺水肿或肺上皮和/或内皮细胞坏死的药物。

著录项

  • 公开/公告号EP3882023A1

    专利类型

  • 公开/公告日2021-09-22

    原文格式PDF

  • 申请/专利权人 SUN YAT-SEN UNIVERSITY;

    申请/专利号EP20200864323

  • 申请日2020-02-01

  • 分类号B32B27/02;B32B27/36;B32B27/18;B32B27/40;B32B27/12;B32B27/08;B32B7/12;B32B33;B29C65/52;A61L31/12;A61L31/14;

  • 国家 EP

  • 入库时间 2022-08-24 21:11:04

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