首页> 外国专利> USE OF 3-(4-HYDROXYPHENYL)PROPIONIC ACID IN PREPARATION OF DRUGS FOR PREVENTING AND TREATING RESPIRATORY TRACT INFECTION

USE OF 3-(4-HYDROXYPHENYL)PROPIONIC ACID IN PREPARATION OF DRUGS FOR PREVENTING AND TREATING RESPIRATORY TRACT INFECTION

机译:使用3-(4-羟基苯基)丙酸在制备用于预防和治疗呼吸道感染的药物中

摘要

Novel pharmaceutical use of 3-(4-Hydroxyphenyl)propionic acid. It is proved through experiments that 3-(4-Hydroxyphenyl)propionic acid has a remarkable pharmacological effect on inhibiting respiratory tract infection, in particular on inhibiting pulmonary edema, inflammatory cell infiltration, and cell apoptosis in lung injury and delaying lung function degradation of mice. Therefore, use of 3-(4-Hydroxyphenyl)propionic acid in preparation of drugs for preventing and treating respiratory tract infection, in particular pneumonia, pulmonary edema or pulmonary epithelial and/or endothelial cell necrosis in lung injury is disclosed for the first time.
机译:新型药物用途3-(4-羟基苯基)丙酸。通过实验证明,3-(4-羟基苯基)丙酸对抑制呼吸道感染具有显着的药理学作用,特别是抑制肺水肿,炎症细胞浸润和细胞凋亡,延迟肺功能降解小鼠的肺部功能。因此,首次公开了使用3-(4-羟基苯基)丙酸在制备用于预防和治疗呼吸道感染的药物中的药物,特别是肺损伤中的肺损伤中的肺炎,肺水肿或肺上皮和/或内皮细胞坏死。

著录项

  • 公开/公告号WO2021151259A1

    专利类型

  • 公开/公告日2021-08-05

    原文格式PDF

  • 申请/专利权人 SUN YAT-SEN UNIVERSITY;

    申请/专利号WO2020CN74148

  • 申请日2020-02-01

  • 分类号A61K31/192;A61P31/04;A61P11;

  • 国家 CN

  • 入库时间 2022-08-24 20:23:27

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