首页> 外国专利> PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NK/T-CELL LYMPHOMA OR NK-CELL LEUKEMIA, COMPRISING PHOSPHODIESTERASE TYPE 5 INHIBITOR

PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING NK/T-CELL LYMPHOMA OR NK-CELL LEUKEMIA, COMPRISING PHOSPHODIESTERASE TYPE 5 INHIBITOR

机译:用于预防或处理NK / T细胞淋巴瘤或NK细胞白血病的药物组合物,包含磷酸二酯酶类型5抑制剂

摘要

The present invention relates to: a pharmaceutical composition for preventing or treating NK/T-cell lymphoma, comprising a phosphodiesterase type 5 inhibitor, the pharmaceutical composition being for inhibiting the reactivation of the Epstein–Barr virus (EBV) induced by a HDAC inhibitor; an anticancer therapy adjuvant composition; and a health functional food. By using the pharmaceutical composition for preventing, alleviating or treating NK/T-cell lymphoma, according to the present invention, EBV reactivation, induced by a HDAC inhibitor used as an anticancer agent for NK/T-cell lymphoma, may be inhibited, and thus side-effects of the HDAC inhibitor may be reduced, and an anticancer effect may be notably increased. Thus, the present invention may be widely used in the pharmaceutical industry on the basis of said effects.
机译:本发明涉及:用于预防或处理NK / T细胞淋巴瘤的药物组合物,其包含磷酸二酯酶类型5抑制剂,该药物组合物用于抑制HDAC抑制剂诱导的Epstein-Barr病毒(EBV)的再活化; 抗癌治疗辅助组合物; 和健康功能食品。 通过使用用于预防,减轻或处理NK / T细胞淋巴瘤的药物组合物,根据本发明,由用作NK / T细胞淋巴瘤的抗癌剂的HDAC抑制剂诱导的EBV再活化,并且可以抑制,并且 因此,可以减少HDAC抑制剂的副作用,并且可以显着增加抗癌效果。 因此,本发明可以基于所述效果广泛用于制药行业。

著录项

  • 公开/公告号WO2021182897A1

    专利类型

  • 公开/公告日2021-09-16

    原文格式PDF

  • 申请/专利权人 SAMSUNG LIFE PUBLIC WELFARE FOUNDATION;

    申请/专利号WO2021KR03044

  • 发明设计人 KIM WON SEOG;PARK CHAE HWA;KIM JOO HYUN;

    申请日2021-03-11

  • 分类号A61K31/519;A61K31/53;A61K31/4985;A61K31/522;A61K31/506;A61K31/167;A61K31/18;A61P35/02;

  • 国家 KR

  • 入库时间 2022-08-24 21:07:43

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