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NEW DIHYDRO-CHINAZOLINONE CONDITIONS OR PHARMACOLOGICAL UNCLOSED SALTS THEREOF AND CELL GROWTH ENGINEER

机译:新的二氢 - Chinazolinone条件或其药理学未缩放的盐和细胞生长工程师

摘要

Provided is a cell proliferation inhibitor comprising a compound of the formula (1) or a pharmacologically acceptable salt thereof:wherein J1and J2each represent CH or N, with the proviso that J1and J2are not simultaneously CH; r represents 0 to 4; each R101is the same or different when r is 2 or more, and R101represents a C1-6alkyl group optionally substituted with a halogen atom or the like; s represents 0 to 5; each R102is the same or different when s is 2 or more, and R102represents a halogen atom or the like; R103represents a hydrogen atom, a C1-6alkyl group, a C3-6cycloalkyl group, or a C3-6cycloalkyl C1-6alkyl group; and R101and R103are optionally linked together to form a five- to seven-membered ring hetero ring when R101is present at the 8-position.
机译:提供一种细胞增殖抑制剂,其包含式(1)的化合物或其药理学上可接受的盐:其中J1和J2ECH代表CH或N,与J1和J2ARA同时不同时CH; R代表0到4; 当R为2或更多时,每个R101是相同或不同的,并且R101RESENTS任选地被卤原子等取代的C1-6烷基; s表示0到5; 当S为2或更多时,每个R102都是相同或不同的,并且R102RESPERS卤原子等; R103Resents氢原子,C1-6烷基,C 3-6环烷基或C3-6环烷烯基-6-6烷基; 并且R101和R103得到任选地连接在一起,以在8位存在于8位的R101的r101时形成五到七元环杂环。

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