The composition includes a first composition, a second composition and a third composition. The first composition comprises an edible ingredient from a fruit, seed, or other part of a plant; the second composition comprises bitter gourd, a first oligosaccharides, a first fermentable dietary fiber, or a combination thereof; and the third composition comprises a second oligosaccharide and a second fermentable dietary fiber. The composition is used to target and restore the structural balance of the gut microbiota and relief of chronic inflammation.
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