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GENETIC CASSETTE COMPRISING THE PHT PATHWAY GENES, RECOMBINANT HOST CELLS COMPRISING IT AND THEIR USE IN THE DEGRADATION AND VALORIZATION OF PHTHALATES
GENETIC CASSETTE COMPRISING THE PHT PATHWAY GENES, RECOMBINANT HOST CELLS COMPRISING IT AND THEIR USE IN THE DEGRADATION AND VALORIZATION OF PHTHALATES
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机译:包含PHT途径基因的遗传盒,包含它的重组宿主细胞及其在邻苯二甲酸盐的降解和瓣膜中使用
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摘要
The present invention provides a recombinant genetic cassette which comprises the catabolic genes involved in the pht pathway as well as an SBP-dependent secondary transporter that are essential for microbial phthalate degradation. The invention also relates to recombinant host cells comprising this cassette and are useful for the aerobic or anaerobic biodegradation of phthalates, preferably o-phthalate (PAs), and for the bioconversion of PAs towards the biosynthesis of value-added biodegradable polymers, such as polyhydroxyalkanoates (PHAs), preferably polyhydroxybutyrates (PHBs).
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