USE OF A GROUP OF MARKERS FOR DIAGNOSING AND ADJUSTING TREATMENT OF PRIMARY BILIARY CHOLANGITIS, PHARMACEUTICAL COMPOSITION AND SOLID DOSAGE FORM FOR TREATING PRIMARY BILIARY CHOLANGITIS

摘要

The invention relates to the field of medicine, in particular to the diagnosis and treatment of primary biliary cholangitis. Proposed is the use of a group of markers: IL-6, Nf-kB, MCP-1/CCL2, Bcl-2 for diagnosing and adjusting treatment of primary biliary cholangitis. Also proposed are the determination of a treatment regimen for primary biliary cholangitis, as well as a pharmaceutical composition and a solid dosage form for treating primary biliary cholangitis, which contain ursodeoxycholic acid and obeticholic acid.