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TARGETED EPIGENETIC THERAPY AGAINST DISTAL REGULATORY ELEMENT OF TGFB2 EXPRESSION
TARGETED EPIGENETIC THERAPY AGAINST DISTAL REGULATORY ELEMENT OF TGFB2 EXPRESSION
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机译:针对TGFB2表达的远端调节因素的靶向表观遗传疗法
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摘要
The instant disclosure provides methods and compositions for the diagnosis, treatment and prevention of a TGFβ2-associated disease, disorder and/or condition, including, e.g., Scleroderma, other fibrotic disease, grade 4 glioblastoma (GBM) and/or Primary Open-Angle Glaucoma (POAG). The disclosure further provides pharmaceutical compositions and kits for the diagnosis, treatment and prevention of TGFβ2-associated diseases, disorders and/or conditions.
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