NK cell activating fusion protein, NK cell and pharmaceutical composition containing them

摘要

The present invention relates to a fusion protein for cancer treatment and a use thereof.The fusion protein for preventing or treating cancer of the present invention comprises a fusion polypeptide comprising: an antibody or fragment thereof binding to a tumor-associated antigen; a linker; and a NK cell-inducing protein of CXCL16, wherein a co-administration of the fusion polypeptide along with the NK cells, an immunocyte therapeutic agent, greatly increases an influx of the NK cells into cancer expressing a certain antigen, thereby having a remarkable effect on preventing or treating cancer.