PLK1 Composition for preventing improving or treating cancer comprising inhibitor of PLK1

摘要

The present invention relates to a biphenyl compound that inhibits PLK1 activity, an isomer thereof, or a pharmaceutically acceptable salt thereof, and a composition for preventing, improving or treating cancer or an anticancer adjuvant comprising the same. The biphenyl compound of the present invention, an isomer thereof or a pharmaceutically acceptable salt thereof binds to the PBD domain with high affinity, and can significantly inhibit the survival of cancer cells, so as to prevent, improve, or treat cancer as a composition for cancer prevention, improvement or treatment as an anticancer adjuvant can be used effectively.