PLK1 Pharmaceutical compositions for preventing or treating cancers comprising the PLK1 inhibitor

摘要

The present invention relates to a pharmaceutical composition for preventing, treating or alleviating cancer, containing an activation Inhibitor of PLK1 as an active component. The compound according to the present invention selectively binds to PBD of PLK1, thereby having advantages of high selectivity and binding affinity for PLK1, and low toxicity. Therefore, a PLK1 activation inhibitor compound according to the present invention can be effectively used as an anticancer agent by inhibiting the growth of various cancer cells, and can be expected to exhibit synergistic effects with existing developed anticancer agents through co-administration, in addition to individual administration thereof.