Heterogeneous combination Prime: boosting therapy and treatment

摘要

This disclosure provides a funmington virus, which is formulated to induce mammalian immune responses to tumor associated antigens.Farmington viruses can express antigenic proteins, including epitopes from tumor associated antigens.Farmington virus can be formulated with a composition that is distinct from an antigenic protein that contains an epitope from tumor associated antigens.The present disclosure also provides Prime: boost therapy for use in inducing the immune response of mammals.The boost comprises a composition comprising a Farmington virus or a Farmington virus.Diagram