Pleioolide derivatives as splenosensory targeting agents for cancer therapy

摘要

The present disclosure provides a pladienolide compound, a pharmaceutical composition containing such compounds, and a pladienolide compound for use in medical treatment methods.These compounds may be useful in the treatment of cancers known in the art, particularly for the purpose of targeting cancer, particularly spliceosomes and mutations.The present invention also provides a pladienolide compound for use in a method of treating cancer by administering at least one pradienolide compound and at least one additional therapy disclosed herein.No selection