SYSTEM AND METHOD FOR GASTRIC ELECTRICAL STIMULATION USING COMPOUND NERVE ACTION POTENTIAL FEEDBACK

摘要

A gastric electric stimulation (GES) system is disclosed which includes a processing system, and at least one of a left vagus nerve sensor (L/R Sensors) and a right vagus nerve sensor coupled to the processing system, the processing system is configured to receive a model which statistically correlates sensed compound nerve action potential (CNAP) parameters measured from at least one of left and right vagus nerves of subjects within a population to feedback surveys of the subjects corresponding to a plurality of gastric symptoms and symptom parameters, receive one or more gastric symptoms of a subject outside of the population (Subject_out), determine CNAP parameters that correspond to the gastric symptoms with least severity (CNAP_min), measure CNAP activity of the Subject_out from the L/R sensors while modifying GES parameters for the Subject_out, select the GES parameters that corresponds to the CNAP_min (GES_out), and output the GES_out.