BOTANICAL COMPOSITIONS OF SALVIA OFFICINALIS WITH ACTIVITY IN EXTENDING CHRONOLOGICAL LIFESPAN AND USES THEREOF

摘要

Compositions comprising a nutritionally or pharmaceutically effective dosage of an extract of Salvia officinalis and an acceptable carrier are provided. The compositions show particular potential in the treatment of age-related pathologies in humans or animals. The extracts are obtained from varieties and cultivars of Salvia officinalis that possess a unique chemical fingerprint that includes unusually low thujone content in the leaf. When tested in C. elegans screening assays compositions that comprise the extract elicit an increase in mean chronological lifespan (CLS) in the C. elegans population of at least 10%.