LIPIDS FOR LIPID NANOPARTICLE DELIVERY OF ACTIVE AGENTS

摘要

Compounds are provided having the following structure: (I) or a pharmaceutically acceptable salt, tautomer or stereoisomer thereof, wherein G¹, R¹, R², L, and n are as defined herein. Use of the compounds as a component of lipid nanoparticle formulations for delivery of a therapeutic agent, compositions comprising the compounds and methods for their use and preparation are also provided.