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Use of SHROOM3 in chronic kidney disease and chronic allograft nephropathy
Use of SHROOM3 in chronic kidney disease and chronic allograft nephropathy
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机译:在慢性肾病和慢性同种异体移植肾病中使用Shroom3
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摘要
A method for identifying the risk of developing Chronic Allograft Nephropathy (CAN) in a patient that received a kidney transplant from a donor which comprises identifying the race of the donor; determining the levels of SHROOM 3 expression in a kidney biopsy specimen obtained from the patient at a predetermined time after transplant; comparing the level of SHROOM 3 expression in the biopsy specimen with the levels of SHROOM 3 expression in a control; determining if the level of SHROOM 3 expression in the allograft is significantly higher than in the control, and diagnosing the patient as being at risk for CAN if the level of SHROOM 3 expression in the specimen is significantly higher than in the control.
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