PLANT PRODUCED BOVINE PAPILLOMAVIRUS VIRUS-LIKE PARTICLES AND PSEUDOVIRIONS

摘要

Methods of producing bovine papillomavirus (BPV) virus-like particles and/or pseudovirions in plant cells have been identified. In some embodiments the methods can be used to produce plant-produced BPV VLPs and pseudovirions. Further provided are pharmaceutical compositions comprising the plant produced BPV VLPs and pseudovirions. In some embodiments the plant-produced BPV VLPs and pseudovirions, or the pharmaceutical compositions may be useful in neutralisation assays.