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NOVEL IMMUNOTHERAPY AGAINST SEVERAL TUMORS INCLUDING NEURONAL AND BRAIN TUMORS

机译:针对几种肿瘤,包括神经元和脑肿瘤的新型免疫疗法

摘要

The present invention relates to peptides, nucleic acids and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer. The present invention furthermore relates to tumor-associated cytotoxic T cell (CTL) peptide epitopes, alone or in combination with other tumor-associated peptides that serve as active pharmaceutical ingredients of vaccine compositions that stimulate anti-tumor immune responses. The present invention relates to 30 peptide sequences and their variants derived from HLA class I and class II molecules of human tumor cells that can be used in vaccine compositions for eliciting anti-tumor immune responses.
机译:本发明涉及用于免疫治疗方法的肽,核酸和细胞。 特别地,本发明涉及癌症的免疫疗法。 本发明还涉及肿瘤相关的细胞毒性T细胞(CTL)肽表位,单独或与其他肿瘤相关肽的组合,其用作刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分。 本发明涉及30个肽序列及其衍生自HLA A类和人肿瘤细胞的II类分子的肽序列及其可可用于引发抗肿瘤免疫反应的疫苗组合物中的II类分子。

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