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METHOD FOR PREDICTING THE RECURRENCE OF AN NON-DEVELOPED PREGNANCY IN PATIENTS WITH PERSISTENT VIRAL INFECTION

机译:预测持续性病毒感染患者未发育妊娠复发的方法

摘要

FIELD: medicine. ;SUBSTANCE: invention relates to medicine, namely to obstetrics and gynecology, and concerns a method for predicting the recurrence of non-developing pregnancy (NDP) in patients with persistent viral infection. The essence of the method: in the venous blood of a patient with a history of an undeveloped pregnancy that developed against the background of a mixed persistent viral infection, in the first week after spontaneous menstruation that occurred in the post-abortion period, two parameters of the interferon status, serum IFN and induced IFNα are determined once by an immunological method. If the level of serum IFN is below 2.0 U/ml and the level of induced IFNα is below 670 U/ml, the risk of relapse of an undeveloped pregnancy is predicted. ;EFFECT: method has simplicity and high prognostic accuracy; the prediction of pathology is possible in the first week after spontaneous menstruation, which occurred after vacuum aspiration of NDP from the uterine cavity, which contributes to the early start of pathogenetic therapy; clinical application of the method will ensure adequate pathogenetic therapy and prevent adverse pregnancy outcomes. ;1 cl, 4 ex
机译:领域:医学。物质:发明涉及医学,即妇产科,并且涉及预测持续性病毒感染患者的非发育妊娠(NDP)复发的方法。该方法的本质:在患者的静脉血液中,患有未发育的妊娠的历史,其在混合持续性病毒感染的背景下,在堕胎后期发生的自发月经后的第一周,两个参数在干扰素状态下,通过免疫方法确定一次血清IFN和诱导的IFNα。如果血清IFN的水平低于2.0 U / mL,并且诱导的IFNα水平低于670 u / mL,则预测未开发的妊娠的复发风险。 ;效果:方法具有简单性和高预后的准确性;在自发月经后的第一周,在从子宫腔的真空吸入后发生的第一周,可以在发育中的患者的早期开始,这有助于致病性疗法的早期开始;该方法的临床应用将确保充分的致病治疗和防止妊娠不良结果。 ; 1 cl,4 ex

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