COMPOSITION FOR PREVENTING OR TREATING PULMONARY DISEASES COMPRISING HYALURONAN AND PROTEOGLYCAN LINK PROTEIN 1

摘要

Provided are a recombinant hyaluronan and proteoglycan link protein 1 (HAPLN1), and a composition for preventing or treating pulmonary diseases, the composition comprising at least one selected from the group consisting of HAPLN1 (hyaluronan and proteoglycan link protein 1) protein, a gene coding for the HAPLN 1 protein, and an effective agent for promoting the expression or activating the functions of HAPLN 1 protein or gene as an active ingredient. The recombinant HAPLN 1 according to the present disclosure may have superior effects of improving alveolar damage caused by aging or elastin reduction, and thus may effectively prevent or treat pulmonary diseases, such as chronic bronchitis, asthma, emphysema, and chronic obstructive pulmonary disease.