A novel combination of tubulin polymerization inhibitors and poly (ADP ribose) polymerase (PARP) inhibitors for use in cancer therapy

摘要

This study relates to a novel combination of tubulin polymerization inhibitors and poly (ADP ribose) polymerase (PARP) inhibitors for use in the treatment of cancer.Solution: a tubulin polymerization inhibitor such as a compound of formula I or a pharmaceutically acceptable salt thereof, and a poly (ADP ribose) polymerase (PARP) inhibitor or a pharmaceutically acceptable salt are used to treat and prevent cancer And / or a method of delay and / or combination therapy of cancer is provided.No selection