首页> 外国专利> Novel aminoalkanoic acid derivative compound introduced with a biphenyl group and antifungal pharmaceutical composition comprising the same

Novel aminoalkanoic acid derivative compound introduced with a biphenyl group and antifungal pharmaceutical composition comprising the same

机译:用双苯基和抗真菌药物组合物引入新型氨基烷酸衍生物化合物和包含相同的抗真菌药物组合物

摘要

The present invention relates to functional derivatives of amino acids alanine and proline for the purpose of providing novel derivatives, salts and/or solvates thereof in which a biphenyl group is introduced into aminoalkanoic acids. The compounds of the present invention have been found to have very good antifungal and fungicidal effects. In addition, it was confirmed that it exhibits a synergistic effect when administered in combination with an existing antifungal agent. In addition, the compounds of the present invention exhibited activity against a wide range of fungi. Accordingly, the compounds of the present invention may be widely used in fields requiring the treatment of antifungal or fungicidal agents against human and animal infectious fungi, and phytopathogenic fungi.
机译:本发明涉及氨基酸丙氨酸和脯氨酸的功能衍生物,目的是提供新的衍生物,盐和/或其溶剂化物,其中将联烯基引入氨基烷烯酸中。 已发现本发明的化合物具有非常好的抗真菌和杀真菌作用。 此外,证实它在与现有的抗真菌剂组合施用时表现出协同效应。 此外,本发明的化合物表现出针对各种真菌的活性。 因此,本发明的化合物可以广泛用于需要治疗抗真菌或杀真菌剂免受人和动物传染性真菌和植物致病性真菌的领域。

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