An object of the present invention is to provide a chemotherapy using a PI3K/AKT/mTOR inhibitor that exhibits excellent antitumor effect on cancer patients. Chemotherapy using an anti-tumor agent containing a PI3K/AKT/mTOR inhibitor in a cancer patient based on the expression level of PHLDA1 and/or PIK3C2B in a biological sample containing tumor cells collected from a cancer patient How to predict the effectiveness of treatment.
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