Negative Microparticles Separator Based on Magnetophoresis and Microparticles Separating Method Using the Same

摘要

The present invention relates to an apparatus for separating microparticles of a negative collection method using magnetophoresis and a separation method thereof, comprising: an unbound magnetic particle capture device for selectively capturing and removing magnetic particles not bound to cells in advance; A first microparticle separation device that primarily separates and removes non-target cells to which magnetic particles are bound while the sample passing through the binding magnetic particle trapping device passes through a microfluidic channel with a high flow rate, and the first microparticle separation device Including a second microparticle separation device that secondarily separates and removes non-target cells to which magnetic particles are bound while the sample passing through the microfluidic channel passes through a microfluidic channel with a slower flow rate, regardless of whether the target cells are expressing antigens or not. It is possible to collect, and there is an effect that can be separated quickly with excellent efficiency.